By Mohsen A. Hedaya
Knowledge of pharmacokinetics is important to realizing the absorption, distribution, metabolism, and excretion of substances. it really is as a result important to these engaged within the discovery, improvement, and preclinical and scientific overview of gear, in addition to practitioners fascinated about the scientific use of gear. utilizing varied methods obtainable to a wide selection of readers, Basic Pharmacokinetics: moment variation demonstrates the quantitative pharmacokinetic relatives and the interaction among pharmacokinetic parameters.
After a simple advent to pharmacokinetics and its comparable fields, the ebook examines:
- Mathematical operations everyday in pharmacokinetics
- Drug distribution and clearance and the way they impact the speed of drug removing after a unmarried dose
- Factors affecting drug absorption following extravascular drug management, the speed and quantity of drug absorption, and drug bioequivalence
- The steady-state suggestion in the course of consistent expense intravenous infusion and through a number of drug administration
- Renal drug removal, drug metabolism, multicompartment types, nonlinear pharmacokinetics, and drug management by way of intermittent intravenous infusion
- Pharmacokinetic-pharmacodynamic modeling, noncompartmental pharmacokinetic information research, clearance idea from the physiological viewpoint, and physiological modeling
- Clinical purposes of pharmacokinetics, together with healing drug tracking, drug pharmacokinetics in distinct populations, pharmacokinetic drug-drug interactions, pharmacogenomics, and purposes of desktops in pharmacokinetics
Accompanying the e-book is a CD-ROM with self-instructional tutorials and pharmacokinetic and pharmacokinetic-pharmacodynamic simulations, permitting visualization of strategies for superior comprehension. This studying software obtained an award from the yank organization of faculties of Pharmacy for innovation in educating, making it a useful complement to this crucial text.
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